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UBP21 Rabbit pAb

-YN3171

主要信息
Target

UBP21

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB

MW

60kD (Observed)

Conjugate/Modification

Unmodified

货号: YN3171
规格
价格
货期
数量
200μL
¥3,780.00
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0

100μL
¥2,300.00
现货

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40μL
¥960.00
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of UBP21 at Human/Mouse/Rat
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
60kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human UBP21 AA range: 50-100
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特异性:
This antibody detects endogenous levels of UBP21 at Human/Mouse/Rat
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基因名称:
USP21 USP23 PP1490
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蛋白名称:
UBP21
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别名:
Ubiquitin carboxyl-terminal hydrolase 21 ;
Deubiquitinating enzyme 21 ;
Ubiquitin thioesterase 21 ;
Ubiquitin-specific-processing protease 21 ;
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数据库链接:
Organism 基因 ID SwissProt
Human 27005; Q9UK80;
Mouse 30941; Q9QZL6;
Rat 688466; B2GUX4;
背景:
This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016],
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功能:
Catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,Function:Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.,similarity:Belongs to the peptidase C19 family. USP21 subfamily.,tissue specificity:Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung.,
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细胞定位:
Cytoplasm . Nucleus .
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组织表达:
Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung.
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研究领域:
>>Necroptosis
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货号: YN3171
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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