DR6 Rabbit pAb
-YN2293
主要信息
Target
DR6
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
72kD (Observed)
Conjugate/Modification
Unmodified
货号: YN2293
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
TNR21 Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
72kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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RS0002
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β-actin (PTR2364) Mouse mAb
YM3028
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YM3029
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human protein . at AA range: 430-510
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特异性:
TNR21 Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
TNFRSF21 DR6 UNQ437/PRO868
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蛋白名称:
Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358)
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别名:
Tumor necrosis factor receptor superfamily member 21 ;
Death receptor 6 ;
CD antigen CD358 ;
Death receptor 6 ;
CD antigen CD358 ;
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背景:
This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013],
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功能:
Caution:It is uncertain whether Met-1 or Met-25 is the initiator.,Function:May activate NF-kappa-B and JNK and promote apoptosis.,similarity:Contains 1 death domain.,similarity:Contains 4 TNFR-Cys repeats.,subunit:Associates with TRADD.,tissue specificity:Highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. Detected at lower levels in lung, skeletal muscle, kidney, testis, uterus, small intestine, colon, spleen, bone marrow and fetal liver. Very low levels were found in adult liver and peripheral blood leukocytes.,
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细胞定位:
Cell membrane ; Single-pass type I membrane protein .
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组织表达:
Detected in fetal spinal cord and in brain neurons, with higher levels in brain from Alzheimer disease patients (at protein level). Highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. Detected at lower levels in lung, skeletal muscle, kidney, testis, uterus, small intestine, colon, spleen, bone marrow and fetal liver. Very low levels were found in adult liver and peripheral blood leukocytes.
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研究领域:
>>Cytokine-cytokine receptor interaction
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文献引用（{{totalcount}}）
货号: YN2293
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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