GPNMB Rabbit pAb
-YN2202
主要信息
Target
GPNMB
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
62kD (Observed)
Conjugate/Modification
Unmodified
货号: YN2202
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
GPNMB Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
62kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from part region of human protein
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特异性:
GPNMB Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
GPNMB HGFIN NMB UNQ1725/PRO9925
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蛋白名称:
Transmembrane glycoprotein NMB (Transmembrane glycoprotein HGFIN)
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背景:
glycoprotein nmb(GPNMB) Homo sapiens The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
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功能:
developmental stage:Expression in poorly metastatic melanoma cell lines; no expression in highly metastatic melanoma cell lines.,Function:Could be a melanogenic enzyme.,similarity:Belongs to the Pmel-17/NMB family.,similarity:Contains 1 PKD domain.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,tissue specificity:Not restricted to the melanocytic lineage.,
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细胞定位:
Cell membrane; Single-pass type I membrane protein . Melanosome membrane ; Single-pass type I membrane protein . Early endosome membrane ; Single-pass type I membrane protein . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
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文献引用（{{totalcount}}）
货号: YN2202
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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