BAMBI Rabbit pAb
-YN2010
主要信息
Target
BAMBI
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
28kD (Observed)
Conjugate/Modification
Unmodified
货号: YN2010
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
BAMBI Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
28kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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YM3028
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抗原&靶点信息
免疫原:
Synthesized peptide derived from part region of human protein
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特异性:
BAMBI Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
BAMBI NMA
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蛋白名称:
BMP and activin membrane-bound inhibitor homolog (Non-metastatic gene A protein) (Putative transmembrane protein NMA)
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背景:
BMP and activin membrane bound inhibitor(BAMBI) Homo sapiens This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008],
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功能:
developmental stage:Expression in poorly metastatic human melanoma cell lines; no expression in highly metastatic human melanoma cell lines.,Function:Negatively regulates TGF-beta signaling.,similarity:Belongs to the BAMBI family.,tissue specificity:High expression in kidney medulla, placenta and spleen; low in kidney cortex, liver, prostate and gut. Not expressed in normal skin, expression is high in melanocytes and in 3 out of 11 melanoma metastases tested.,
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细胞定位:
Membrane ; Single-pass type I membrane protein .
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组织表达:
High expression in kidney medulla, placenta and spleen; low in kidney cortex, liver, prostate and gut. Not expressed in normal skin, expression is high in melanocytes and in 3 out of 11 melanoma metastases tested.
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研究领域:
>>Wnt signaling pathway ;
>>TGF-beta signaling pathway
>>TGF-beta signaling pathway
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信号通路
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货号: YN2010
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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