ING5 Rabbit pAb
-YN1846
主要信息
Target
ING5
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
26kD (Observed)
Conjugate/Modification
Unmodified
货号: YN1846
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
ING5 Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
26kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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RS0002
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Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
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GAPDH (PTR2304) Mouse mAb
YM3029
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抗原&靶点信息
免疫原:
Synthesized peptide derived from part region of human protein
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特异性:
ING5 Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
ING5
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蛋白名称:
Inhibitor of growth protein 5 (p28ING5)
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背景:
This gene encodes a tumor suppressor protein that inhibits cell growth and induces apoptosis. This protein contains a PHD-type zinc finger. It interacts with tumor suppressor p53 and p300, a component of the histone acetyl transferase complex, suggesting a role in transcriptional regulation. Alternative splicing and the use of multiple promoters and 3' terminal exons results in multiple transcript variants. [provided by RefSeq, Aug 2016],
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功能:
Function:Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator.,similarity:Belongs to the ING family.,similarity:Contains 1 PHD-type zinc finger.,subunit:Component of the HBO1 complex composed at least of ING4 or ING5, MYTS2/HBO1, EAF6, and one of PHF15, PHF16 and PHF17. Component of the MOZ/MORF composed at least of ING5, MYST3/MOZ, MYST4/MORF and one of BRPF1, BRD1/BRPF2 and BRPF3. Interacts with EP300 and TP53.,
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细胞定位:
Nucleus . Chromosome . Localizes to transcription start sites. .
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组织表达:
Down-regulated in bone marrow cells in acute myeloid leukemia patients as compared with normal bone marrow cells.
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文献引用（{{totalcount}}）
货号: YN1846
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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