GRP3 Rabbit pAb
-YN1155
主要信息
Target
GRP3
Host Species
Rabbit
Reactivity
Human
Applications
WB, ELISA
MW
75kD (Observed)
Conjugate/Modification
Unmodified
货号: YN1155
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
GRP3 Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
75kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human protein . at AA range: 90-170
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特异性:
GRP3 Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
RASGRP3 GRP3 KIAA0846
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蛋白名称:
Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1)
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背景:
RAS guanyl releasing protein 3(RASGRP3) Homo sapiens Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008],
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功能:
Function:Guanine nucleotide exchange factor (GEF) for Ras and Rap1.,similarity:Belongs to the RASGRP family.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 Ras-GEF domain.,similarity:Contains 2 EF-hand domains.,
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细胞定位:
intracellular,plasma membrane,integral component of plasma membrane,guanyl-nucleotide exchange factor complex,perinuclear region of cytoplasm,
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组织表达:
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研究领域:
>>MAPK signaling pathway ;
>>Ras signaling pathway ;
>>Rap1 signaling pathway ;
>>B cell receptor signaling pathway ;
>>Pathways in cancer
>>Ras signaling pathway ;
>>Rap1 signaling pathway ;
>>B cell receptor signaling pathway ;
>>Pathways in cancer
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信号通路
Organismal Systems >> Immune system >> B cell receptor signaling pathway
Human Diseases >> Cancer: overview >> Pathways in cancer
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Environmental Information Processing >> Signal transduction >> Ras signaling pathway
Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway
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货号: YN1155
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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