Synthesized peptide derived from part region of human protein

PA24F Polyclonal Antibody detects endogenous levels of protein.

PLA2G4F

Cytosolic phospholipase A2 zeta (cPLA2-zeta) (Phospholipase A2 group IVF)

catalytic activity:Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.,domain:The N-terminal C2 domain associates with lipid membranes and mediates its regulation by presenting the active site to its substrate in response to elevations of cytosolic Ca(2+).,enzyme regulation:Stimulated by cytosolic Ca(2+).,function:Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Has higher enzyme activity for phosphatidylethanolamine than phosphatidylcholine.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PLA2c domain.,subcellular location:Translocates to lysosomal membranes in a calcium-dependent fashion.,

Catalytic activity:Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.,Domain:The N-terminal C2 domain associates with lipid membranes and mediates its regulation by presenting the active site to its substrate in response to elevations of cytosolic Ca(2+).,enzyme regulation:Stimulated by cytosolic Ca(2+).,Function:Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Has higher enzyme activity for phosphatidylethanolamine than phosphatidylcholine.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PLA2c domain.,subcellular location:Translocates to lysosomal membranes in a calcium-dependent fashion.,

Cytoplasm, cytosol . Cell membrane ; Peripheral membrane protein . Mitochondrion .

>>Glycerophospholipid metabolism ;
>>Ether lipid metabolism ;
>>Arachidonic acid metabolism ;
>>Linoleic acid metabolism ;
>>alpha-Linolenic acid metabolism ;
>>Metabolic pathways ;
>>MAPK signaling pathway ;
>>Ras signaling pathway ;
>>Phospholipase D signaling pathway ;
>>Necroptosis ;
>>Vascular smooth muscle contraction ;
>>VEGF signaling pathway ;
>>Platelet activation ;
>>Fc epsilon RI signaling pathway ;
>>Fc gamma R-mediated phagocytosis ;
>>Glutamatergic synapse ;
>>Serotonergic synapse ;
>>Long-term depression ;
>>Inflammatory mediator regulation of TRP channels ;
>>GnRH signaling pathway ;
>>Ovarian steroidogenesis ;
>>Oxytocin signaling pathway ;
>>Choline metabolism in cancer