ADA33 Rabbit pAb
-YN0410
主要信息
Target
ADA33
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
89kD (Observed)
Conjugate/Modification
Unmodified
货号: YN0410
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
ADA33 Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
89kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human protein . at AA range: 200-280
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特异性:
ADA33 Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
ADAM33 C20orf153 UNQ873/PRO1891
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蛋白名称:
Disintegrin and metalloproteinase domain-containing protein 33 (ADAM 33) (EC 3.4.24.-)
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背景:
ADAM metallopeptidase domain 33(ADAM33) Homo sapiens This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013],
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功能:
cofactor:Binds 1 zinc ion per subunit.,Disease:Defects in ADAM33 may be a cause of susceptibility to asthma.,Domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,PTM:The precursor is cleaved by a furin endopeptidase.,similarity:Contains 1 disintegrin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 peptidase M12B domain.,tissue specificity:Expressed in all tissues, except liver, with high expression in placenta, lung, spleen and veins.,
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细胞定位:
Membrane; Single-pass type I membrane protein.
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组织表达:
Expressed in all tissues, except liver, with high expression in placenta, lung, spleen and veins.
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文献引用（{{totalcount}}）
货号: YN0410
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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