developmental stage:Highly expressed in the fetal brain.,Domain:A conserved motif AVN[ED]CD within the disintegrin-like domain could be involved in the binding to the integrin receptor.,Function:May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.,similarity:Contains 1 disintegrin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 peptidase M12B domain.,subunit:Ligand for integrin alpha-V/beta-3.,tissue specificity:Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole.,
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