developmental stage:Synthesized during maturation of epidermal keratinocytes.,Function:Probably contributes to terminal cornification.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,sequence Caution:Translated as Glu.,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins.,
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