UPB1 (PT0799R) PT™ Rabbit mAb
-YM8894
主要信息
Target
UPB1
Host Species
Rabbit
Reactivity
Human
Applications
WB, IHC, IP
MW
42kD (Observed)
Conjugate/Modification
Unmodified
货号: YM8894
规格
价格
货期
数量
200μL
￥3,780.00
一周
0
100μL
￥2,300.00
一周
0
40μL
￥960.00
一周
0
加入购物车
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详细信息
推荐稀释比
WB 1:1000-5000; IHC 1:100-300; IP 1:50-100
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
实测条带
42kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0799R
同种型
IgG,Kappa
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
UPB1;BUP1
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蛋白名称:
Beta-ureidopropionase;BUP-1;Beta-alanine synthase;N-carbamoyl-beta-alanine amidohydrolase;
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别名:
UPB1 ;
BUP1 ;
Beta-ureidopropionase ;
BUP-1 ;
Beta-alanine synthase ;
N-carbamoyl-beta-alanine amidohydrolase ;
BUP1 ;
Beta-ureidopropionase ;
BUP-1 ;
Beta-alanine synthase ;
N-carbamoyl-beta-alanine amidohydrolase ;
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背景:
This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq, Jul 2008]
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功能:
Catalyzes a late step in pyrimidine degradation (PubMed:22525402, PubMed:24526388). Converts N-carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide (PubMed:10415095, PubMed:10542323, PubMed:11508704, PubMed:22525402, PubMed:24526388, PubMed:29976570). Likewise, converts N-carbamoyl-beta-aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide (Probable). {ECO:0000269|PubMed:10415095, ECO:0000269|PubMed:10542323, ECO:0000269|PubMed:11508704, ECO:0000269|PubMed:22525402, ECO:0000269|PubMed:24526388, ECO:0000269|PubMed:29976570, ECO:0000305|PubMed:22525402, ECO:0000305|PubMed:24526388}.
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细胞定位:
Cytoplasm.
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组织表达:
Detected in liver (at protein level). {ECO:0000269|PubMed:22525402}.
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文献引用（{{totalcount}}）
货号: YM8894
规格
价格
货期
数量
200μL
￥3,780.00
一周
0
100μL
￥2,300.00
一周
0
40μL
￥960.00
一周
0
加入购物车
已收藏
收藏
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