BMP-2 (PT0362R) PT™ Rabbit mAb
-YM8215
主要信息
Target
BMP-2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat,
Applications
WB, IHC, IF, IP, ELISA
MW
45kD,13kD (Calculated)
30kD,13kD (Observed)
Conjugate/Modification
Unmodified
货号: YM8215
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
45kD,13kD
实测条带
30kD,13kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0362R
同种型
IgG,Kappa
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
特异性:
Endogenous
展开内容
基因名称:
BMP2
展开内容
蛋白名称:
Bone morphogenetic protein 2
展开内容
别名:
BMP2 ;
BMP2A ;
Bone morphogenetic protein 2 ;
BMP-2 ;
Bone morphogenetic protein 2A ;
BMP-2A
BMP2A ;
Bone morphogenetic protein 2 ;
BMP-2 ;
Bone morphogenetic protein 2A ;
BMP-2A
展开内容
背景:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016],
展开内容
功能:
Function:Induces cartilage and bone formation.,online information:Bone morphogenetic protein 2 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked. Interacts with GREM2 (By similarity) and SOSTDC1.,tissue specificity:Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.,
展开内容
细胞定位:
Secreted
展开内容
组织表达:
Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
展开内容
研究领域:
>>Cytokine-cytokine receptor interaction ;
>>TGF-beta signaling pathway ;
>>Hippo signaling pathway ;
>>Pathways in cancer ;
>>Basal cell carcinoma
>>TGF-beta signaling pathway ;
>>Hippo signaling pathway ;
>>Pathways in cancer ;
>>Basal cell carcinoma
展开内容
信号通路
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Cancer: specific types >> Basal cell carcinoma
Environmental Information Processing >> Signal transduction >> TGF-beta signaling pathway
Environmental Information Processing >> Signal transduction >> Hippo signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
文献引用（{{totalcount}}）
货号: YM8215
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}