Synthesized peptide derived from human p120 Catenin AA range: 600-700

The antibody can specifically recognize human p120 catenin protein.

CTNND1 KIAA0384

Cadherin associated Src substrate;Cadherin-associated Src substrate;CAS;Catenin (cadherin associated protein) delta 1;Catenin delta 1;Catenin delta;Catenin delta-1;CTND1_HUMAN;CTNND 1;CTNND;CTNND1;delta 1 Catenin;KIAA0384;p120;P120 CAS;p120 catenin;P120 CTN;p120 (cas) ;p120 (ctn) ;P120CAS;P120CTN

Cadherin associated Src substrate ;
Cadherin-associated Src substrate ;
CAS ;
Catenin ;
cadherin associated protein ;
delta 1 ;
Catenin delta 1 ;
Catenin delta ;
Catenin delta-1 ;
CTND1_HUMAN ;
CTNND 1 ;
CTNND ;
CTNND1 ;
delta 1 Catenin ;
KIAA0384 ;
p120 ;
P120 CAS ;
p120 catenin ;
P120 CTN ;
p120 ;
cas ;
p120 ;
ctn ;
P120CAS ;
P120CTN

catenin delta 1 (CTNND1) Homo sapiens This gene encodes a member of the Armadillo protein family , which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq , Dec 2010] ,

Alternative products:Experimental confirmation may be lacking for some isoforms ,Disease:May contribute to cell malignancy. Complete loss of expression was observed in approximately 10% of invasive ductal breast carcinomas investigated. ,Domain:A possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted. ,Function:Binds to and inhibits the transcriptional repressor ZBTB33 , which may lead to activation of target genes of the Wnt signaling pathway (By similarity) . May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF , PDGF , CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage. ,induction:Induced in vascular endothelium by wounding. This effect is potentiated by prior laminar shear stress , which enhances wound closure. ,PTM:Phosphorylated. ,similarity:Belongs to the beta-catenin family. ,similarity:Contains 10 ARM repeats. ,subcellular location:Interaction with GLIS2 promotes nuclear translocation. ,subunit:Belongs to a multiprotein cell-cell adhesion complex that also contains E-cadherin , alpha-catenin , beta-catenin , and gamma-catenin. Binds to the C-terminal fragment of PSEN1 and mutually competes for E-cadherin. Interacts with ZBTB33. Interacts with GLIS2. ,tissue specificity:Expressed in vascular endothelium. ,

Cytoplasmic , Membranous

>>Rap1 signaling pathway ;
>>Adherens junction ;
>>Leukocyte transendothelial migration