TRAP (ABT522) Mouse mAb (Ready to Use)
-YM6915R
主要信息
Target
TRAP
Host Species
Mouse
Reactivity
Human
Applications
IHC
Conjugate/Modification
Unmodified
详细信息
推荐稀释比
Ready to use for IHC
组成
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
特异性
The antibody can specifically recognize human TRAP protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
2°C to 8°C/1 year,Ship by ice bag
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT522
同种型
IgG1, Kappa
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human TRAP AA range: 250-325
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特异性:
The antibody can specifically recognize human TRAP protein.
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基因名称:
ACP5
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蛋白名称:
TRAP
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别名:
Tartrate-resistant acid phosphatase type 5 ;
TR-AP ;
Tartrate-resistant acid ATPase ;
TrATPase ;
Type 5 acid phosphatase ;
TR-AP ;
Tartrate-resistant acid ATPase ;
TrATPase ;
Type 5 acid phosphatase ;
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背景:
This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L (+) -tartrate. [provided by RefSeq , Aug 2008] ,
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功能:
Catalytic activity:A phosphate monoester + H (2) O = an alcohol + phosphate. ,cofactor:Binds 2 iron ions per subunit. ,Disease:This relatively minor intracellular isozyme of acid phosphatase can become the dominant isozyme in certain pathological states (Gaucher and Hodgkin diseases , the hairy cell , the B-cell , and the T-cell leukemias) . ,similarity:Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family. ,subunit:Exists either as monomer or , after proteolytic processing , as a dimer of two chains linked by disulfide bond (s) . ,
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细胞定位:
Cytoplasmic
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组织表达:
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研究领域:
>>Riboflavin metabolism ;
>>Metabolic pathways ;
>>Lysosome ;
>>Osteoclast differentiation ;
>>Rheumatoid arthritis
>>Metabolic pathways ;
>>Lysosome ;
>>Osteoclast differentiation ;
>>Rheumatoid arthritis
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