Arginase-1 (ABT-Arg1) Mouse mAb (Ready to Use)
-YM6684R
主要信息
Target
Arginase I
Host Species
Mouse
Reactivity
Human
Applications
IHC
Conjugate/Modification
Unmodified
详细信息
推荐稀释比
Ready to use for IHC
组成
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
特异性
The antibody can specifically recognize human Arginase-1 protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
2°C to 8°C/1 year,Ship by ice bag
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT-Arg1
同种型
IgG2b, Kappa
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
Synthesized peptide derived from human Arginase-1 AA range: 200-322
展开内容
特异性:
The antibody can specifically recognize human Arginase-1 protein.
展开内容
基因名称:
ARG1
展开内容
蛋白名称:
Arginase-1 (Liver-type arginase) (Type I arginase)
展开内容
背景:
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution , subcellular localization , immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene , is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia , an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq , Sep 2011] ,
展开内容
功能:
Catalytic activity:L-arginine + H (2) O = L-ornithine + urea. ,cofactor:Binds 2 manganese ions per subunit. ,Disease:Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid , and periodic hyperammonemia occurs. Clinical manifestations include developmental delay , seizures , mental retardation , hypotonia , ataxia , progressive spastic quadriplegia. ,induction:By arginine or homoarginine. ,online information:Arginase entry ,pathway:Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1. ,similarity:Belongs to the arginase family. ,subunit:Homotrimer. ,
展开内容
细胞定位:
Nuclear , Cytoplasmic
展开内容
研究领域:
>>Arginine biosynthesis ;
>>Arginine and proline metabolism ;
>>Metabolic pathways ;
>>Biosynthesis of amino acids ;
>>Amoebiasis
>>Arginine and proline metabolism ;
>>Metabolic pathways ;
>>Biosynthesis of amino acids ;
>>Amoebiasis
展开内容
文献引用（{{totalcount}}）
Recently Viewed Products
Clear all
×
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}