This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions , including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability , and is a diagnostic marker for some human diseases , including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq , Jun 2010] ,
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