SOX9 (ABT-SOX9) Mouse mAb
-YM6546
主要信息
Target
Sox-9
Host Species
Mouse
Reactivity
Human, Mouse, Rat, Bovine
Applications
IHC, ELISA
MW
56kD (Calculated)
70kD (Observed)
Conjugate/Modification
Unmodified
货号: YM6546
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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已收藏
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详细信息
推荐稀释比
IHC 1:200-400; ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
The antibody can specifically recognize human SOX9 protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
理论分子量
56kD
实测条带
70kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT-SOX9
同种型
IgG2b, Kappa
相关产品
Primary Antibodies
SOX9 (ABT-SOX9) Mouse mAb (Ready to Use)
YM6546R
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Primary Antibodies
SOX9 Rabbit pAb
YT4371
预览→
Primary Antibodies
SOX9 (Phospho Ser181) Rabbit pAb
YP0895
预览→
Primary Antibodies
SOX9 (ABT-SOX9) Mouse mAb
YM6546
预览→
ELISA Kits
Total SOX9 Cell-Based Colorimetric ELISA Kit
KA4286C
预览→
ELISA Kits
SOX9 (Phospho Ser181) Cell-Based Colorimetric ELISA Kit
KA1336C
预览→
抗原&靶点信息
免疫原:
Synthesized peptide derived from human SOX9 AA range: 1-100
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特异性:
The antibody can specifically recognize human SOX9 protein.
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基因名称:
SOX9
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蛋白名称:
Transcription factor SOX-9
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背景:
SRY-box 9 (SOX9) Homo sapiens The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and , with steroidogenic factor 1 , regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia , frequently with sex reversal. [provided by RefSeq , Jul 2008] ,
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功能:
Disease:Defects in SOX9 are the cause of campomelic dysplasia (CMD1) [MIM:114290]. CMD1 is a rare , often lethal , dominantly inherited , congenital osteochondrodysplasia , associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones , unusually small scapulae , deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate , micrognatia , flat face and hypertelorism are common. Various defects of the ear are often evident , affecting the cochlea , malleus incus , stapes and tympanum. Most patients die soon after birth due to respiratory distress which has been attributed to hypoplasia of the tracheobronchial cartilage and small thoracic cage. ,Function:Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. ,similarity:Contains 1 HMG box DNA-binding domain. ,
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细胞定位:
Nuclear
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组织表达:
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研究领域:
>>cAMP signaling pathway
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文献引用（{{totalcount}}）
货号: YM6546
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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