Parathyroid Hormone (PTH) (ABT-PTH) Mouse mAb (Ready to Use)
-YM6471R
主要信息
Target
Parathyroid Hormone
Host Species
Mouse
Reactivity
Human
Applications
IHC
Conjugate/Modification
Unmodified
详细信息
推荐稀释比
Ready to use for IHC
组成
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
特异性
The antibody can specifically recognize human Parathyroid Hormone protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
2°C to 8°C/1 year,Ship by ice bag
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT-PTH
同种型
IgG1, Kappa
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Parathyroid Hormone (PTH) (ABT-PTH) Mouse mAb (Ready to Use)
YM6471R
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human Parathyroid Hormone (PTH) AA range: 50-115
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特异性:
The antibody can specifically recognize human Parathyroid Hormone protein.
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基因名称:
PTH
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蛋白名称:
Parathyroid hormone (PTH) (Parathormone) (Parathyrin)
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背景:
This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein , known as hyperparathyroidism , can result in hypercalcemia and kidney stones. On the other hand , defective processing of the encoded protein may lead to hypoparathyroidism , which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. [provided by RefSeq , Oct 2015] ,
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功能:
Disease:Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. ,Function:PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. ,online information:Parathyroid hormone entry ,similarity:Belongs to the parathyroid hormone family. ,
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细胞定位:
Cytoplasmic , Membranous
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研究领域:
>>Neuroactive ligand-receptor interaction ;
>>Parathyroid hormone synthesis , secretion and action ;
>>Endocrine and other factor-regulated calcium reabsorption ;
>>Rheumatoid arthritis
>>Parathyroid hormone synthesis , secretion and action ;
>>Endocrine and other factor-regulated calcium reabsorption ;
>>Rheumatoid arthritis
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