Synthesized peptide derived from human Cytokeratin 5 and Cytokeratin 6 AA range: C terminal amino acids 500-590 of Cytokeratin 5 and N terminal amino acids 2-100 of Cytokeratin 6

The antibody can recognize both human CK5 and CK6 protein, and shows no cross reaction with other typies of cytokeratin.

KRT5 KRT6A KRT6B KRT6C

Keratin； type II cytoskeletal 5 ；58 kDa cytokeratin；Cytokeratin-5；CK-5；Keratin-5；K5；Type-II keratin Kb5；type II cytoskeletal 6A;Cytokeratin-6A; CK-6A; Keratin-6A; K6A; Type-II keratin Kb6; allergen Hom s 5; type II cytoskeletal 6B;Cytokeratin-6B; CK-6B; Keratin-6B; K6B; type II cytoskeletal 6C;Cytokeratin-6C; CK-6C; Keratin-6C; K6C

58 kDa cytokeratin ;
CK-5 ;
CK5 ;
Cytokeratin-5 ;
Cytokeratin5 ;
DDD ;
DDD1 ;
EBS2 ;
epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types ;
K2C5_HUMAN ;
K5 ;
keratin 5 ;
epidermolysis bullosa simplex,Dowling-Meara/Kobner/Weber-Cockayne types ;
Keratin 5 ;
Keratin ;
keratin complex 2,basic,gene 5 ;
keratin,type II cytoskeletal 5 ;
Keratin-5 ;
Keratin5 ;
KRT 5 ;
Krt5 ;
KRT5A ;
type II cytoskeletal 5 ;
Type-II keratin Kb5 ;
CK 6A ;
CK 6B ;
CK 6C ;
CK 6D ;
CK 6E ;
CK-6B ;
CK-6C ;
CK-6E ;
Cytokeratin 6a ;
Cytokeratin 6B ;
Cytokeratin 6C ;
Cytokeratin 6D ;
Cytokeratin 6E ;
Cytokeratin-6B ;
Cytokeratin-6C ;
Cytokeratin-6E ;
K2C6C_HUMAN ;
K6a keratin ;
K6b keratin ;
K6C ;
K6c keratin ;
K6d keratin ;
K6e keratin ;
Keratin ;
Keratin K6h ;
Keratin type II cytoskeletal 6A ;
Keratin type II cytoskeletal 6B ;
Keratin type II cytoskeletal 6C ;
Keratin type II cytoskeletal 6D ;
Keratin type II cytoskeletal 6E ;
Keratin-6C ;
KRT6A ;
KRT6B ;
KRT6C ;
KRT6D ;
KRT6E ;
type II cytoskeletal 6C ;
Type-II keratin Kb12 ;
58 kDa cytokeratin antibody ;
CK-5 antibody ;
CK5 antibody ;
Cytokeratin-5 antibody ;
Cytokeratin5 antibody ;
DDD antibody ;
DDD1 antibody ;
EBS2 antibody ;
epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types antibody ;
K2C5_HUMAN antibody ;
K5 antibody ;
keratin 5 ;
epidermolysis bullosa simplex,Dowling-Meara/Kobner/Weber-Cockayne types ;
antibody ;
Keratin 5 antibody ;
Keratin antibody ;
keratin complex 2,basic,gene 5 antibody ;
keratin,type II cytoskeletal 5 antibody ;
Keratin-5 antibody ;
Keratin5 antibody ;
KRT 5 antibody ;
Krt5 antibody ;
KRT5A antibody ;
type II cytoskeletal 5 antibody ;
Type-II keratin Kb5 antibody

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells , which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins , including K9-K23 , and the hair keratins Ha1-Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins , including K1-K8 , and the hair keratins , Hb1-Hb6. This antibody can react with Cytokeratin 5 and Cytokeratin 6.

Function: Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress (By similarity) . Regulates the recruitment of Langerhans cells to the epidermis , potentially by modulation of the abundance of macrophage chemotactic cytokines , macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity) . Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding , while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.

Cytoplasmic , Membranous

>>Signal Transduction ;
>>Cytoskeleton / ECM ;
>>Cytoskeleton ;
>>Intermediate Filaments ;
>>Class I ;
>>Cytokeratins