Synaptophysin (ABT533) Mouse mAb (Ready to Use)
-YM6105R
主要信息
Target
Synaptophysin
Host Species
Mouse
Reactivity
Human, Mouse, Rat, Bovine
Applications
IHC
Conjugate/Modification
Unmodified
详细信息
推荐稀释比
Ready to use for IHC
组成
The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300
特异性
The antibody can specifically recognize human Synaptophysin protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
2°C to 8°C/1 year,Ship by ice bag
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT533
同种型
IgG1, Kappa
相关产品
Primary Antibodies
Synaptophysin Rabbit pAb
YT4500
预览→
ELISA Kits
Total SYP Cell-Based Colorimetric ELISA Kit
KA3385C
预览→
抗原&靶点信息
免疫原:
Synthesized peptide derived from human Synaptophysin AA range: 200-313
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特异性:
The antibody can specifically recognize human Synaptophysin protein.
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基因名称:
SYP
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蛋白名称:
Major synaptic vesicle protein p38;MRX96;MRXSYP;Syn p38;Synaptophysin;Syp;SYPH;SYPH_HUMAN;SypI
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别名:
Major synaptic vesicle protein p38 ;
MRX96 ;
MRXSYP ;
Syn p38 ;
Synaptophysin ;
Syp ;
SYPH ;
SYPH_HUMAN ;
SypI
MRX96 ;
MRXSYP ;
Syn p38 ;
Synaptophysin ;
Syp ;
SYPH ;
SYPH_HUMAN ;
SypI
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背景:
This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR) . [provided by RefSeq , Aug 2011] ,
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功能:
Domain:The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein. ,Function:Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. ,online information:Synaptophysin entry ,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. ,similarity:Belongs to the synaptophysin/synaptobrevin family. ,similarity:Contains 1 MARVEL domain. ,subunit:Homohexamer or homotetramer. ,tissue specificity:Characteristic of a type of small (30-80 nm) neurosecretory vesicles , including presynaptic vesicles , but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype. ,
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细胞定位:
Cytoplasmic
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组织表达:
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