CD21 (ABT-CD21) Mouse mAb
-YM6013
主要信息
Target
CD21
Host Species
Mouse
Reactivity
Human
Applications
IHC, ELISA
MW
113kD (Calculated)
160kD (Observed)
Conjugate/Modification
Unmodified
货号: YM6013
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
IHC 1:50-200; ELISA 1:500-5000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
The antibody can specifically recognize human CD21 protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
理论分子量
113kD
实测条带
160kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT-CD21
同种型
IgG1, Kappa
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human CD21 AA range: 400-500
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特异性:
The antibody can specifically recognize human CD21 protein.
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基因名称:
CR2 C3DR
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蛋白名称:
Complement receptor type 2 (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD antigen CD21)
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背景:
This gene encodes a membrane protein , which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) . Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq , Sep 2009] ,
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功能:
Disease:Genetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) [MIM:610927]. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory , and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin , joints , kidneys , and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. ,Function:Receptor for complement C3Dd , for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. ,similarity:Belongs to the receptors of complement activation (RCA) family. ,similarity:Contains 15 Sushi (CCP/SCR) domains. ,tissue specificity:Mature B-lymphocytes , T-lymphocytes , pharyngeal epithelial cells , astrocytes and follicular dendritic cells of the spleen. ,
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细胞定位:
Membranous
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研究领域:
>>Complement and coagulation cascades ;
>>Hematopoietic cell lineage ;
>>B cell receptor signaling pathway ;
>>Epstein-Barr virus infection
>>Hematopoietic cell lineage ;
>>B cell receptor signaling pathway ;
>>Epstein-Barr virus infection
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信号通路
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货号: YM6013
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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