GAP43 (Mix) Mouse mAb
-YM3379
主要信息
Target
GAP-43
Host Species
Mouse
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF
MW
38,43kD (Observed)
Conjugate/Modification
Unmodified
货号: YM3379
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:1000-2000; IHC 1:200-500; IF 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
特异性
The antibody detects endogenous GAP-43 protein.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
实测条带
38,43kD
修饰
Unmodified
克隆性
Monoclonal
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抗原&靶点信息
免疫原:
Recombinant Protein of GAP-43
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特异性:
The antibody detects endogenous GAP-43 protein.
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基因名称:
GAP43
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蛋白名称:
Neuromodulin
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别名:
GAP43 ;
Neuromodulin ;
Axonal membrane protein GAP-43 ;
Growth-associated protein 43 ;
Neural phosphoprotein B-50 ;
pp46
Neuromodulin ;
Axonal membrane protein GAP-43 ;
Growth-associated protein 43 ;
Neural phosphoprotein B-50 ;
pp46
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背景:
The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
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功能:
Function:This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons.,online information:Gap-43 entry,PTM:Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity.,similarity:Belongs to the neuromodulin family.,similarity:Contains 1 IQ domain.,subcellular location:Cytoplasmic surface of growth cone and synaptic plasma membranes.,subunit:Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.,
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细胞定位:
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, growth cone membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, synapse . Cell projection, filopodium membrane ; Peripheral membrane protein . Perikaryon . Cell projection, dendrite . Cell projection, axon . Cytoplasm . Cytoplasmic surface of growth cone and synaptic plasma membranes. .
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组织表达:
Alzheimer cortex,Brain,Subthalamic nucleus,
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文献引用（{{totalcount}}）
货号: YM3379
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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