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β I tubulin Mouse mAb

-YM3119

2 5
主要信息
Target

Tubulin β

Host Species

Mouse

Reactivity

Zebrafish

Applications

WB

MW

50kD (Observed)

Conjugate/Modification

Unmodified

详细信息
推荐稀释比
WB 1:500-10000
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
特异性
The antibody detects Zebrafish endgenousβ I tubulin proteins.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
实测条带
50kD
修饰
Unmodified
克隆性
Monoclonal
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抗原&靶点信息
免疫原:
Synthetic Peptide of β I tubulin
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特异性:
The antibody detects Zebrafish endgenousβ I tubulin proteins.
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基因名称:
TUBB1
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蛋白名称:
Tubulin beta-1 chain
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别名:
TUBB1 ;
Tubulin beta-1 chain ;
TUBB2A ;
TUBB2 ;
Tubulin beta-2A chain ;
TUBB2B ;
Tubulin beta-2B chain ;
TUBB4B ;
TUBB2C ;
Tubulin beta-4B chain ;
Tubulin beta-2 chain ;
Tubulin beta-2C chain ;
TUBB3 ;
TUBB4 ;
Tubulin beta-3 chain ;
Tubulin beta-4 chain ;
Tubulin beta-III ;
TUBB4A ;
TUBB4 ;
TUBB5 ;
Tubulin beta-4A chain ;
Tubulin 5 beta ;
Tubulin beta-4 chain ;
TUBB ;
TUBB5 ;
OK/SW-cl.56 ;
Tubulin beta chain ;
Tubulin beta-5 chain ;
TUBB6 ;
Tubulin beta-6 chain ;
TUBB8 ;
Tubulin beta-8 chain
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数据库链接:
Organism 基因 ID SwissProt
Human 81027; Q9H4B7;
Mouse 545486; A2AQ07;
背景:
This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010],
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功能:
Function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,
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细胞定位:
Cytoplasm, cytoskeleton .
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组织表达:
Hematopoietic cell-specific. Major isotype in leukocytes, where it represents 50% of all beta-tubulins.
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研究领域:
>>Phagosome ;
>>Gap junction ;
>>Alzheimer disease ;
>>Parkinson disease ;
>>Amyotrophic lateral sclerosis ;
>>Huntington disease ;
>>Prion disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Pathogenic Escherichia coli infection ;
>>Salmonella infection
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