Kif 7 (3F8) Mouse mAb
-YM3063
主要信息
Target
Kif 7
Host Species
Mouse
Reactivity
Human, Mouse, Rat
Applications
IHC, IF
Conjugate/Modification
Unmodified
货号: YM3063
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:50-200; IF 1:50-200
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
特异性
The antibody detects endogenous Kif 7 proteins.
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
修饰
Unmodified
克隆性
Monoclonal
克隆号
3F8
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抗原&靶点信息
免疫原:
Synthetic Peptide of Kif 7
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特异性:
The antibody detects endogenous Kif 7 proteins.
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基因名称:
KIF7
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蛋白名称:
Kinesin-like protein KIF7
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别名:
Kinesin-like protein KIF7
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背景:
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011],
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功能:
similarity:Belongs to the kinesin-like protein family. KIF27 subfamily.,similarity:Contains 1 kinesin-motor domain.,tissue specificity:Embryonic stem cells, melanotic melanoma and Jurkat T-cells.,
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细胞定位:
Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Localizes to the cilium tip.
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组织表达:
Embryonic stem cells, melanotic melanoma and Jurkat T-cells. Expressed in heart, lung, liver, kidney, testis, retina, placenta, pancreas, colon, small intestin, prostate and thymus.
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研究领域:
>>Hedgehog signaling pathway ;
>>Pathways in cancer ;
>>Basal cell carcinoma
>>Pathways in cancer ;
>>Basal cell carcinoma
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信号通路
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货号: YM3063
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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