Purified recombinant fragment of Tyro3 expressed in E. Coli.

Tyro3 Monoclonal Antibody detects endogenous levels of Tyro3 protein.

TYRO3

Tyrosine-protein kinase receptor TYRO3

TYRO3 ;
BYK ;
DTK ;
RSE ;
SKY ;
Tyrosine-protein kinase receptor TYRO3 ;
Tyrosine-protein kinase DTK ;
Tyrosine-protein kinase RSE ;
Tyrosine-protein kinase SKY ;
Tyrosine-protein kinase byk

The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010],

Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,Function:May be involved in cell adhesion processes, particularly in the central nervous system. In case of filovirus infection, seems to function as a cell entry factor.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Monomer and homodimer. Interacts with GAS6.,tissue specificity:Abundant in the brain and lower levels in other tissues.,

Cell membrane; Single-pass type I membrane protein.

Abundant in the brain and lower levels in other tissues.