GDF-8 Mouse mAb
-YM0303
主要信息
Target
GDF-8
Host Species
Mouse
Reactivity
Human
Applications
WB, ELISA
MW
43kD (Calculated)
Conjugate/Modification
Unmodified
货号: YM0303
规格
价格
货期
数量
200μL
￥5,880.00
一周
0
100μL
￥3,200.00
一周
0
50μL
￥2,000.00
一周
0
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详细信息
推荐稀释比
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
GDF-8 Monoclonal Antibody detects endogenous levels of GDF-8 protein.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
43kD
修饰
Unmodified
克隆性
Monoclonal
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抗原&靶点信息
免疫原:
Purified recombinant fragment of GDF-8 expressed in E. Coli.
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特异性:
GDF-8 Monoclonal Antibody detects endogenous levels of GDF-8 protein.
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基因名称:
MSTN
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蛋白名称:
Growth/differentiation factor 8
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别名:
MSTN ;
GDF8 ;
Growth/differentiation factor 8 ;
GDF-8 ;
Myostatin
GDF8 ;
Growth/differentiation factor 8 ;
GDF-8 ;
Myostatin
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背景:
myostatin(MSTN) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016],
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功能:
Function:Acts specifically as a negative regulator of skeletal muscle growth.,online information:Myostatin entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked (By similarity). Interacts with WFIKKN2, leading to inhibit its activity.,
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细胞定位:
Secreted .
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组织表达:
Colon,Muscle,Pericardium,Skeletal muscle,
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研究领域:
>>Cytokine-cytokine receptor interaction
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货号: YM0303
规格
价格
货期
数量
200μL
￥5,880.00
一周
0
100μL
￥3,200.00
一周
0
50μL
￥2,000.00
一周
0
加入购物车
已收藏
收藏
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