CD94 Mouse mAb
-YM0138
主要信息
Target
CD94
Host Species
Mouse
Reactivity
Human
Applications
WB, Flow Cyt, ELISA
MW
21kD (Calculated)
Conjugate/Modification
Unmodified
货号: YM0138
规格
价格
货期
数量
200μL
￥5,880.00
一周
0
100μL
￥3,200.00
一周
0
50μL
￥2,000.00
一周
0
加入购物车
已收藏
收藏
详细信息
推荐稀释比
WB 1:500-1:2000; Flow Cyt 1:200-1:400; ELISA 1:10000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
CD94 Monoclonal Antibody detects endogenous levels of CD94 protein.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
21kD
修饰
Unmodified
克隆性
Monoclonal
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
Purified recombinant fragment of human CD94 expressed in E. Coli.
展开内容
特异性:
CD94 Monoclonal Antibody detects endogenous levels of CD94 protein.
展开内容
基因名称:
KLRD1
展开内容
蛋白名称:
Natural killer cells antigen CD94
展开内容
别名:
KLRD1 ;
CD94 ;
Natural killer cells antigen CD94 ;
KP43 ;
Killer cell lectin-like receptor subfamily D member 1 ;
NK cell receptor ;
CD antigen CD94
CD94 ;
Natural killer cells antigen CD94 ;
KP43 ;
Killer cell lectin-like receptor subfamily D member 1 ;
NK cell receptor ;
CD antigen CD94
展开内容
背景:
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
展开内容
功能:
Function:Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.,online information:CD94,similarity:Contains 1 C-type lectin domain.,subunit:Can form disulfide-bonded heterodimer with NKG2 family members.,tissue specificity:Natural killer cells.,
展开内容
细胞定位:
Cell membrane ; Single-pass type II membrane protein .
展开内容
组织表达:
Expressed in NK cell subsets (at protein level) (PubMed:21825173, PubMed:9430220, PubMed:9485206). Expressed in memory/effector CD8-positive alpha-beta T cell subsets (at protein level) (PubMed:12387742, PubMed:20952657). Expressed in melanoma-specific cytotoxic T cell clones (at protein level) (PubMed:9485206). Expressed in terminally differentiated cytotoxic gamma-delta T cells (at protein level) (PubMed:20952657). KLRD1-KLRC1 and KLRD1-KLRC2 are differentially expressed in NK and T cell populations, with only minor subsets expressing both receptor complexes (at protein level) (PubMed:20952657).
展开内容
研究领域:
>>Antigen processing and presentation ;
>>Natural killer cell mediated cytotoxicity ;
>>Graft-versus-host disease
>>Natural killer cell mediated cytotoxicity ;
>>Graft-versus-host disease
展开内容
信号通路
文献引用（{{totalcount}}）
货号: YM0138
规格
价格
货期
数量
200μL
￥5,880.00
一周
0
100μL
￥3,200.00
一周
0
50μL
￥2,000.00
一周
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}