CD11c (PN0417) Nb-FC recombinant antibody
-YA0531
主要信息
Target
CD11c
Reactivity
Human
Applications
FC, ELISA
Conjugate/Modification
Unmodified
货号: YA0531
规格
价格
货期
数量
200μg
￥3,780.00
两个月
0
100μg
￥2,300.00
两个月
0
40μg
￥960.00
两个月
0
加入购物车
已收藏
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详细信息
推荐稀释比
ELISA 1:5000-100000; Flow Cyt 1-2μg/Test
组成
Phosphate-buffered solution
来源
Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
特异性
This recombinant monoclonal antibody can detects endogenous levels of CD11c protein.
纯化工艺
Recombinant Expression and Affinity purified
储存
-15°C to -25°C/2 year(Avoid freeze / thaw cycles)
浓度
Please check the information on the tube
修饰
Unmodified
克隆号
PN0417
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
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抗原&靶点信息
免疫原:
Purified recombinant Human CD11c
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特异性:
This recombinant monoclonal antibody can detects endogenous levels of CD11c protein.
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基因名称:
ITGAX CD11C
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蛋白名称:
Integrin alpha-X (CD11 antigen-like family member C) (Leu M5) (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (CD antigen CD11c)
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别名:
Integrin alpha-X ;
CD11 antigen-like family member C ;
Leu M5 ;
Leukocyte adhesion glycoprotein p150,95 alpha chain ;
Leukocyte adhesion receptor p150,95 ;
CD antigen CD11c ;
CD11 antigen-like family member C ;
Leu M5 ;
Leukocyte adhesion glycoprotein p150,95 alpha chain ;
Leukocyte adhesion receptor p150,95 ;
CD antigen CD11c ;
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背景:
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013],
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功能:
Domain:The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.,Function:Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 1 VWFA domain.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. Alpha-X associates with beta-2.,tissue specificity:Predominantly expressed in monocytes and granulocytes.,
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细胞定位:
Membrane; Single-pass type I membrane protein.
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信号通路
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货号: YA0531
规格
价格
货期
数量
200μg
￥3,780.00
两个月
0
100μg
￥2,300.00
两个月
0
40μg
￥960.00
两个月
0
加入购物车
已收藏
收藏
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