GPR56 (PN0145) Nb-FC recombinant antibody
-YA0439
主要信息
Target
GPR56
Reactivity
Human
Applications
ELISA, FC
Conjugate/Modification
Unmodified
货号: YA0439
规格
价格
货期
数量
200μg
￥3,780.00
现货
0
100μg
￥2,300.00
现货
0
40μg
￥960.00
现货
0
加入购物车
已收藏
收藏
详细信息
推荐稀释比
ELISA 1:5000-100000; Flow Cyt 1-2μg/Test
组成
Phosphate-buffered solution
来源
Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
特异性
This recombinant monoclonal antibody can detects endogenous levels of GPR56 protein.
纯化工艺
Recombinant Expression and Affinity purified
储存
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度
Please check the information on the tube
修饰
Unmodified
克隆号
PN0145
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
抗原&靶点信息
免疫原:
Purified recombinant Human GPR56
展开内容
特异性:
This recombinant monoclonal antibody can detects endogenous levels of GPR56 protein.
展开内容
基因名称:
ADGRG1 GPR56 TM7LN4 TM7XN1 UNQ540/PRO1083
展开内容
蛋白名称:
Adhesion G-protein coupled receptor G1 (G-protein coupled receptor 56) (Protein TM7XN1) [Cleaved into: ADGRG1 N-terminal fragment (ADGRG1 NT) (GPR56 N-terminal fragment) (GPR56 NT) (GPR56(N)) (GPR56 extracellular subunit) (GPR56 subunit alpha); ADGRG1 C-terminal fragment (ADGRG1 CT) (GPR56 C-terminal fragment) (GPR56 CT) (GPR56(C)) (GPR56 seven-transmembrane subunit) (GPR56 7TM) (GPR56 subunit beta)]
展开内容
别名:
GPR56 ;
TM7LN4 ;
TM7XN1 ;
G-protein coupled receptor 56 ;
Protein TM7XN1 ;
GPR56 nanobody ;
TM7LN4 ;
TM7XN1 ;
G-protein coupled receptor 56 ;
Protein TM7XN1 ;
GPR56 nanobody ;
展开内容
背景:
This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations inThis gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
展开内容
功能:
Disease:Defects in GPR56 are the cause of bilateral frontoparietal polymicrogyria (BFPP) [MIM:606854]. BFPP is characterized by disorganized cortical lamination that is most severe in frontal cortex.,Could be involved in cell-cell interactions.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,tissue specificity:Widely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells.,
展开内容
细胞定位:
Cell membrane ; Multi-pass membrane protein .; [ADGRG1 N-terminal fragment]: Secreted .; [ADGRG1 C-terminal fragment]: Membrane raft . Interaction with its ligand COL3A1 leads to the release of ADGRG1 NT from the membrane and triggers the association of ADGRG1 CT with lipid rafts. .
展开内容
组织表达:
Widely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells. Expression is down-regulated in different tumors from highly metastatic cells.
展开内容
文献引用（{{totalcount}}）
货号: YA0439
规格
价格
货期
数量
200μg
￥3,780.00
现货
0
100μg
￥2,300.00
现货
0
40μg
￥960.00
现货
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}