CD166 (PN0223) Nb-FC recombinant antibody
-YA0207
主要信息
Target
CD166
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
货号: YA0207
规格
价格
货期
数量
200μg
￥3,780.00
现货
0
100μg
￥2,300.00
现货
0
40μg
￥960.00
现货
0
加入购物车
已收藏
收藏
详细信息
推荐稀释比
ELISA 1:5000-100000
组成
Phosphate-buffered solution
来源
Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
特异性
This recombinant monoclonal antibody can detects endogenous levels of CD166 protein.
纯化工艺
Recombinant Expression and Affinity purified
储存
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度
Please check the information on the tube
修饰
Unmodified
克隆号
PN0223
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
抗原&靶点信息
免疫原:
Purified recombinant Human CD166
展开内容
特异性:
This recombinant monoclonal antibody can detects endogenous levels of CD166 protein.
展开内容
基因名称:
ALCAM MEMD
展开内容
蛋白名称:
CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166)
展开内容
别名:
ALCAM ;
MEMD ;
CD166 antigen ;
Activated leukocyte cell adhesion molecule ;
CD166
MEMD ;
CD166 antigen ;
Activated leukocyte cell adhesion molecule ;
CD166
展开内容
背景:
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain.This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011]
展开内容
功能:
Domain:The CD6 binding site is located in the N-terminal Ig-like domain.,Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Spleen, placenta, liver, and weakly in liver. Expressed by activated T-cells, B-cells, monocytes and thymic epithelial cells. Expressed by neurons in the brain. Restricted expression in tumor cell lines. Preferentially expressed in highly metastasizing melanoma cell lines.,
展开内容
细胞定位:
Cell membrane ; Single-pass type I membrane protein . Cell projection, axon . Cell projection, dendrite . Detected at the immunological synapse, i.e, at the contact zone between antigen-presenting dendritic cells and T-cells (PubMed:15294938, PubMed:16352806). Colocalizes with CD6 and the TCR/CD3 complex at the immunological synapse (PubMed:15294938). .; [Isoform 3]: Secreted .
展开内容
组织表达:
Detected on hematopoietic stem cells derived from umbilical cord blood (PubMed:2474813). Detected on lymph vessel endothelial cells, skin and tonsil (PubMed:23169771). Detected on peripheral blood monocytes (PubMed:154873). Detected on monocyte-derived dendritic cells (at protein level) (PubMed:1635286). Detected at low levels in spleen, placenta, liver (PubMed:952422). Expressed by activated T-cells, B-cells, monocytes and thymic epithelial cells (PubMed:7767). Isoform 1 and isoform 3 are detected in vein and artery endothelial cells, astrocytes, keratinocytes and artery smooth muscle cells (PubMed:15496415). Expressed by neurons in the brain. Restricted expression in tumor cell lines. Detected in highly metastasizing melanoma cell lines (PubMed:952422).
展开内容
文献引用（{{totalcount}}）
货号: YA0207
规格
价格
货期
数量
200μg
￥3,780.00
现货
0
100μg
￥2,300.00
现货
0
40μg
￥960.00
现货
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}