Synthesized peptide derived from human FSH AA range: 1-100

The antibody can specifically recognize human FS H protein, and shows no cross reaction with LH, CG and TSH proteins.

FSHB

Follitropin subunit beta (Follicle-stimulating hormone beta subunit) (FSH-B) (FSH-beta) (Follitropin beta chain)

Follicle Stimulating Hormone ;
Follicle stimulating hormone beta polypeptide ;
Follicle stimulating hormone beta subunit ;
Follitropin beta chain ;
Follitropin subunit beta ;
FSH-B ;
FSH-beta ;
FSHB ;
FSHbeta

follicle stimulating hormone beta subunit (FSHB) Homo sapiens The pituitary glycoprotein hormone family includes follicle-stimulating hormone , luteinizing hormone , chorionic gonadotropin , and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone , follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq , Jul 2008] ,

Disease:Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD) [MIM:229070]. Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility , producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men. ,Function:Stimulates development of follicle and spermatogenesis in the reproductive organs. ,online information:Follicle-stimulating hormone entry ,online information:The Singapore human mutation and polymorphism database ,pharmaceutical:Available under the names Gonal-F or Metrodin HP (Serono) and Puregon (Organon) . Used in the treatment of infertility in women with proven hypopituitarism or who have not responded to clomifene; or in superovulation treatment for assisted conception (such as in vitro fertilization) . Metrodin HP is also used in the treatment of hypogonadotrophic hypogonadism in men for the stimulation of spermatogenesis. ,similarity:Belongs to the glycoprotein hormones subunit beta family. ,subunit:Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin , lutropin , follitropin and gonadotropin. ,

Cytoplasmic

>>cAMP signaling pathway ;
>>Neuroactive ligand-receptor interaction ;
>>GnRH signaling pathway ;
>>Ovarian steroidogenesis