CD141 (ABT145) IHC kit
-IHCM6830
主要信息
Target
CD141
Host Species
Mouse
Conjugate/Modification
Unmodified
货号: IHCM6830
规格
价格
货期
数量
100mL
￥14,800.00
一周
0
10mL
￥1,780.00
一周
0
3mL
￥780.00
一周
0
加入购物车
已收藏
收藏
详细信息
特异性
The antibody can specifically recognize human CD141 protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
2°C to 8°C/1 year,Ship by ice bag
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT145
同种型
IgG2b, Kappa
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
Synthesized peptide derived from human CD141 AA range: 50-150
展开内容
特异性:
The antibody can specifically recognize human CD141 protein.
展开内容
基因名称:
THBD THRM
展开内容
蛋白名称:
CD141
展开内容
别名:
Thrombomodulin ;
TM ;
Fetomodulin ;
CD antigen CD141 ;
TM ;
Fetomodulin ;
CD antigen CD141 ;
展开内容
背景:
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C , which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease , also known as inherited thrombophilia. [provided by RefSeq , Jul 2008] ,
展开内容
功能:
Disease:Defects in THBD are the cause of thrombophilia due to thrombomodulin defect (THR-THBDD) [MIM:188040]. THR-THBDD is a hemostatic disorder characterized by a tendency to thrombosis. ,Function:Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved , protein Ca scissions the activated cofactors of the coagulation mechanism , factor Va and factor VIIIa , and thereby reduces the amount of thrombin generated. ,online information:Thrombomodulin ,online information:Thrombomodulin entry ,PTM:N-glycosylated. ,PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. ,similarity:Contains 1 C-type lectin domain. ,similarity:Contains 6 EGF-like domains. ,tissue specificity:Endothelial cells are unique in synthesizing thrombomodulin. ,
展开内容
细胞定位:
Membranous
展开内容
研究领域:
>>Complement and coagulation cascades ;
>>AGE-RAGE signaling pathway in diabetic complications ;
>>Fluid shear stress and atherosclerosis
>>AGE-RAGE signaling pathway in diabetic complications ;
>>Fluid shear stress and atherosclerosis
展开内容
文献引用（{{totalcount}}）
货号: IHCM6830
规格
价格
货期
数量
100mL
￥14,800.00
一周
0
10mL
￥1,780.00
一周
0
3mL
￥780.00
一周
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
×
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}