Arginase-1 (ABT-Arg1) IHC kit
-IHCM6684
主要信息
Target
Arginase I
Host Species
Mouse
Conjugate/Modification
Unmodified
货号: IHCM6684
规格
价格
货期
数量
100mL
￥14,800.00
一周
0
10mL
￥1,780.00
一周
0
3mL
￥780.00
一周
0
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详细信息
特异性
The antibody can specifically recognize human Arginase-1 protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
2°C to 8°C/1 year,Ship by ice bag
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT-Arg1
同种型
IgG2b, Kappa
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YM3028
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human Arginase-1 AA range: 200-322
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特异性:
The antibody can specifically recognize human Arginase-1 protein.
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基因名称:
ARG1
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蛋白名称:
Arginase-1 (Liver-type arginase) (Type I arginase)
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背景:
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution , subcellular localization , immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene , is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia , an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq , Sep 2011] ,
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功能:
Catalytic activity:L-arginine + H (2) O = L-ornithine + urea. ,cofactor:Binds 2 manganese ions per subunit. ,Disease:Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid , and periodic hyperammonemia occurs. Clinical manifestations include developmental delay , seizures , mental retardation , hypotonia , ataxia , progressive spastic quadriplegia. ,induction:By arginine or homoarginine. ,online information:Arginase entry ,pathway:Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1. ,similarity:Belongs to the arginase family. ,subunit:Homotrimer. ,
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细胞定位:
Nuclear , Cytoplasmic
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研究领域:
>>Arginine biosynthesis ;
>>Arginine and proline metabolism ;
>>Metabolic pathways ;
>>Biosynthesis of amino acids ;
>>Amoebiasis
>>Arginine and proline metabolism ;
>>Metabolic pathways ;
>>Biosynthesis of amino acids ;
>>Amoebiasis
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货号: IHCM6684
规格
价格
货期
数量
100mL
￥14,800.00
一周
0
10mL
￥1,780.00
一周
0
3mL
￥780.00
一周
0
加入购物车
已收藏
收藏
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