Thyroglobulin (PT0653) IHC kit
-IHCM6224
主要信息
Target
Thyroglobulin
Host Species
Mouse
Conjugate/Modification
Unmodified
货号: IHCM6224
规格
价格
货期
数量
100mL
￥14,800.00
一周
0
10mL
￥1,780.00
一周
0
3mL
￥780.00
一周
0
加入购物车
已收藏
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详细信息
特异性
The antibody can specifically recognize human Thyroglobulin protein.
纯化工艺
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存
2°C to 8°C/1 year,Ship by ice bag
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0653
同种型
IgG1, Kappa
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Thyroglobulin Rabbit pAb
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Secondary Antibodies
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Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
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β-actin (PTR2364) Mouse mAb
YM3028
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GAPDH (PTR2304) Mouse mAb
YM3029
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human Thyroglobulin AA range: 2700-2768
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特异性:
The antibody can specifically recognize human Thyroglobulin protein.
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基因名称:
TG
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蛋白名称:
Thyroglobulin
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别名:
Thyroglobulin ;
Tg ;
Tg ;
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背景:
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination , and subsequent thyroxine biosynthesis , in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis , manifested as goiter , and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq , Nov 2009] ,
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功能:
Disease:Defects in TG are a cause of some forms of goiter [MIM:188450]. Goiter is an enlargement of the thyroid gland. This is sometimes linked to hypothyroidism. ,Disease:Variations in TG are associated with susceptibility to autoimmune thyroid disease type 3 (AITD3) [MIM:608175]. AITDs including Graves disease (GD) and Hashimoto thyroiditis (HT) , are among the most common human autoimmune diseases. They are complex diseases , which are caused by an interaction between susceptibility genes and nongenetic factors , such as infection. ,Function:Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) . ,online information:Thyroglobulin entry ,PTM:Sulfated. ,similarity:Belongs to the type-B carboxylesterase/lipase family. ,similarity:Contains 11 thyroglobulin type-1 domains. ,subunit:Homodimer. ,tissue specificity:Thyroid gland specific. ,
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细胞定位:
Cytoplasmic
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组织表达:
研究领域:
>>Thyroid hormone synthesis ;
>>Autoimmune thyroid disease
>>Autoimmune thyroid disease
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货号: IHCM6224
规格
价格
货期
数量
100mL
￥14,800.00
一周
0
10mL
￥1,780.00
一周
0
3mL
￥780.00
一周
0
加入购物车
已收藏
收藏
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