CD223 (LAG-3) (PTF0114) Mouse mAb
-YF0110
主要信息
Target
CD223
Host Species
Mouse
Reactivity
Human
Applications
FC, IF
Conjugate/Modification
Unmodified
详细信息
推荐稀释比
IF 1:200-1:1000; FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
组成
PBS, pH 7.4
特异性
Endogenous
纯化工艺
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
储存
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
浓度
0.5mg/ml
修饰
Unmodified
克隆性
Monoclonal
克隆号
PTF0114
同种型
Mouse IgG1/Kappa
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
LAG3
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蛋白名称:
Lymphocyte activation gene 3 protein
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别名:
LAG3 ;
FDC ;
Lymphocyte activation gene 3 protein ;
LAG-3 ;
Protein FDC ;
CD223
FDC ;
Lymphocyte activation gene 3 protein ;
LAG-3 ;
Protein FDC ;
CD223
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背景:
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008],
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功能:
Function:Involved in lymphocyte activation. Binds to HLA class-II antigens.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:On cell surface of activated NK and T-lymphocytes.,
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细胞定位:
[Lymphocyte activation gene 3 protein]: Cell membrane ; Single-pass type I membrane protein .; [Secreted lymphocyte activation gene 3 protein]: Secreted . Produced following cleavage of the main chain. .
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