详细信息
组成
Liquid in PBS
来源
E.coli
纯度
SDS-PAGE >90%
储存
-20°C/6 month,-80°C for long storage
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
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Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
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Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
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Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
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抗原&靶点信息
序列:
Amino acid: 211-347, with his-MBP tag.
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基因名称:
RPS6KB1
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蛋白名称:
P70S6k protein
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别名:
Ribosomal protein S6 kinase beta-2 ;
S6K-beta-2 ;
S6K2 ;
70 kDa ribosomal protein S6 kinase 2 ;
P70S6K2 ;
p70-S6K 2 ;
S6 kinase-related kinase ;
SRK ;
Serine/threonine-protein kinase 14B ;
p70 ribosomal S6 kinase beta ;
S6K-beta ;
p70 S6 kinase beta ;
p70 S6K-beta ;
p70 S6KB ;
p70-beta ;
S6K-beta-2 ;
S6K2 ;
70 kDa ribosomal protein S6 kinase 2 ;
P70S6K2 ;
p70-S6K 2 ;
S6 kinase-related kinase ;
SRK ;
Serine/threonine-protein kinase 14B ;
p70 ribosomal S6 kinase beta ;
S6K-beta ;
p70 S6 kinase beta ;
p70 S6K-beta ;
p70 S6KB ;
p70-beta ;
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背景:
catalytic activity:ATP + a protein = ADP + a phosphoprotein. ,function:Phosphorylates specifically ribosomal protein S6. ,PTM:Phosphorylated upon DNA damage , probably by ATM or ATR. ,similarity:Belongs to the protein kinase superfamily. ,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. ,similarity:Contains 1 AGC-kinase C-terminal domain. ,similarity:Contains 1 protein kinase domain. ,
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功能:
translation , protein amino acid phosphorylation , phosphorus metabolic process , phosphate metabolic process ,intracellular signaling cascade , protein kinase cascade , phosphorylation , protein kinase B signaling cascade ,
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细胞定位:
Cytoplasm. Nucleus.
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信号通路
Cellular Processes >> Transport and catabolism >> Autophagy - animal
Organismal Systems >> Immune system >> Fc gamma R-mediated phagocytosis
Organismal Systems >> Endocrine system >> Insulin signaling pathway
Organismal Systems >> Aging >> Longevity regulating pathway
Organismal Systems >> Aging >> Longevity regulating pathway - multiple species
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Cancer: overview >> PD-L1 expression and PD-1 checkpoint pathway in cancer
Human Diseases >> Cancer: specific types >> Colorectal cancer
Human Diseases >> Cancer: specific types >> Pancreatic cancer
Human Diseases >> Cancer: specific types >> Hepatocellular carcinoma
Human Diseases >> Cancer: specific types >> Gastric cancer
Human Diseases >> Cancer: specific types >> Acute myeloid leukemia
Human Diseases >> Cancer: specific types >> Breast cancer
Environmental Information Processing >> Signal transduction >> ErbB signaling pathway
Environmental Information Processing >> Signal transduction >> TGF-beta signaling pathway
Environmental Information Processing >> Signal transduction >> Apelin signaling pathway
Environmental Information Processing >> Signal transduction >> HIF-1 signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Environmental Information Processing >> Signal transduction >> AMPK signaling pathway
Environmental Information Processing >> Signal transduction >> mTOR signaling pathway
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