Synthesized peptide derived from human GROβ AA range: 58-107

This antibody detects endogenous levels of Human GROβ

CXCL2 GRO2 GROB MIP2A SCYB2

GROβ

C-X-C motif chemokine 2 ;
Growth-regulated protein beta ;
Gro-beta ;
Macrophage inflammatory protein 2-alpha ;
MIP2-alpha ;
[Cleaved into: GRO-beta ;
5-73 ;
GRO-beta-T ;
Hematopoietic synergistic factor ;
HSF ;
SB-251353 ;
]

function:Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.,online information:CXCL2 entry,pharmaceutical:GRO-beta(5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias.,PTM:The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,

chemotaxis, defense response, inflammatory response, immune response, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, behavior, locomotory behavior, response to wounding, taxis,

Secreted.

>>Cytokine-cytokine receptor interaction ;
>>Viral protein interaction with cytokine and cytokine receptor ;
>>Chemokine signaling pathway ;
>>NF-kappa B signaling pathway ;
>>NOD-like receptor signaling pathway ;
>>IL-17 signaling pathway ;
>>TNF signaling pathway ;
>>Alcoholic liver disease ;
>>Epithelial cell signaling in Helicobacter pylori infection ;
>>Legionellosis ;
>>Amoebiasis ;
>>Kaposi sarcoma-associated herpesvirus infection ;
>>Rheumatoid arthritis ;
>>Lipid and atherosclerosis