Synthetic peptide from human protein at AA range: 65-114

The antibody detects endogenous ENA-78

CXCL5 ENA78 SCYB5

C-X-C motif chemokine 5 (ENA-78(1-78)) (Epithelial-derived neutrophil-activating protein 78) (Neutrophil-activating peptide ENA-78) (Small-inducible cytokine B5) [Cleaved into: ENA-78(8-78); ENA-78(9-78)]

C-X-C motif chemokine 5 ;
ENA-78 ;
1-78 ;
Epithelial-derived neutrophil-activating protein 78 ;
Neutrophil-activating peptide ENA-78 ;
Small-inducible cytokine B5 ;
[Cleaved into: ENA-78 ;
8-78 ;
ENA-78 ;
9-78 ;
]

This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013],

Function:Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes.,online information:CXCL5 entry,PTM:N-terminal processed forms ENA-78(8-78) and ENA-78(9-78) are produced by proteolytic cleavage after secretion from peripheral blood monocytes.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,

Secreted.

Bladder,Epithelium,Kidney,Peripheral blood monocyte,Platelet,

>>Cytokine-cytokine receptor interaction ;
>>Viral protein interaction with cytokine and cytokine receptor ;
>>Chemokine signaling pathway ;
>>IL-17 signaling pathway ;
>>TNF signaling pathway ;
>>Pertussis ;
>>Rheumatoid arthritis