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POLR3B Rabbit pAb

-YT3814

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主要信息
Target

POLR3B

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF, ELISA

MW

128kD (Observed)

Conjugate/Modification

Unmodified

货号: YT3814
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
POLR3B Polyclonal Antibody detects endogenous levels of POLR3B protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
128kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human POLR3B. AA range:321-370
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特异性:
POLR3B Polyclonal Antibody detects endogenous levels of POLR3B protein.
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基因名称:
POLR3B
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蛋白名称:
DNA-directed RNA polymerase III subunit RPC2
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别名:
POLR3B ;
DNA-directed RNA polymerase III subunit RPC2 ;
RNA polymerase III subunit C2 ;
C128 ;
DNA-directed RNA polymerase III 127.6 kDa polypeptide ;
DNA-directed RNA polymerase III subunit B
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数据库链接:
Organism 基因 ID SwissProt
Human 55703; Q9NW08;
Mouse 70428; P59470;
背景:
This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
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功能:
Catalytic activity:Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).,Function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.,similarity:Belongs to the RNA polymerase beta chain family.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.,
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细胞定位:
Nucleus .
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研究领域:
>>RNA polymerase ;
>>Cytosolic DNA-sensing pathway
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货号: YT3814
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询
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