The antiserum was produced against synthesized peptide derived from human IGF-I. AA range:100-149

IGF-I Polyclonal Antibody detects endogenous levels of IGF-I protein.

IGF1

Insulin-like growth factor I

IBP1 ;
IGF-IA ;
IGF1A ;
IGFI ;
insulin-like growth factor 1 ;
insulin-like growth factor IA ;
mechano growth factor ;
MGF ;
somatomedin C

The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015],

Disease:Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.,Function:The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity.,online information:Insulin-like growth factor 1 entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the insulin family.,

extracellular region,extracellular space,plasma membrane,insulin-like growth factor binding protein complex,platelet alpha granule lumen,alphav-beta3 integrin-IGF-1-IGF1R complex,insulin-like growth factor ternary complex,exocytic vesicle,

Brain,Liver,PCR rescued clones,