Cdc37 Rabbit pAb
-YT0805
主要信息
Target
Cdc37
Host Species
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Applications
WB, IHC, IF, ELISA
MW
44kD (Observed)
Conjugate/Modification
Unmodified
货号: YT0805
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Cdc37 Polyclonal Antibody detects endogenous levels of Cdc37 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
44kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human CDC37. AA range:1-50
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特异性:
Cdc37 Polyclonal Antibody detects endogenous levels of Cdc37 protein.
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基因名称:
CDC37
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蛋白名称:
Hsp90 co-chaperone Cdc37
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别名:
CDC37 ;
CDC37A ;
Hsp90 co-chaperone Cdc37 ;
Hsp90 chaperone protein kinase-targeting subunit ;
p50Cdc37
CDC37A ;
Hsp90 co-chaperone Cdc37 ;
Hsp90 chaperone protein kinase-targeting subunit ;
p50Cdc37
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背景:
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008],
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功能:
Function:Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.,PTM:Constitutively sumoylated by UBE2I.,similarity:Belongs to the CDC37 family.,subunit:Forms a complex with Hsp90. Interacts with AR, CDK4, CDK6, EIF2AK1 and RB1.,
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细胞定位:
Cytoplasm .
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组织表达:
Lymph,Placenta,
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研究领域:
>>PI3K-Akt signaling pathway
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文献引用（{{totalcount}}）
货号: YT0805
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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