AIM2 Rabbit pAb
-YT0151
主要信息
Target
AIM2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
39kD (Observed)
Conjugate/Modification
Unmodified
货号: YT0151
规格
价格
货期
数量
200μL
￥3,780.00
一个月
0
100μL
￥2,300.00
一个月
0
40μL
￥960.00
一个月
0
加入购物车
已收藏
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
AIM2 Polyclonal Antibody detects endogenous levels of AIM2 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
39kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human AIM2. AA range:51-100
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特异性:
AIM2 Polyclonal Antibody detects endogenous levels of AIM2 protein.
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基因名称:
AIM2
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蛋白名称:
Interferon-inducible protein AIM2
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别名:
AIM2 ;
Interferon-inducible protein AIM2 ;
Absent in melanoma 2
Interferon-inducible protein AIM2 ;
Absent in melanoma 2
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背景:
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008],
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功能:
Disease:Defects in AIM2 may be a cause of microsatellite unstable colon cancers.,Function:Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.,induction:By interferon gamma.,similarity:Belongs to the HIN-200 family.,similarity:Contains 1 DAPIN domain.,similarity:Contains 1 HIN-200 domain.,subunit:Homodimer.,tissue specificity:Expressed in spleen, small intestine, peripheral blood leukocytes, and testis.,
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细胞定位:
Nucleus. Cytoplasm. Activated inflammasomes can aggregate in the cytosol as speck-like particles.
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组织表达:
Expressed in spleen, small intestine, peripheral blood leukocytes, and testis.
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研究领域:
>>NOD-like receptor signaling pathway ;
>>Cytosolic DNA-sensing pathway
>>Cytosolic DNA-sensing pathway
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信号通路
文献引用（{{totalcount}}）
货号: YT0151
规格
价格
货期
数量
200μL
￥3,780.00
一个月
0
100μL
￥2,300.00
一个月
0
40μL
￥960.00
一个月
0
加入购物车
已收藏
收藏
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