C/EBP α (Phospho Thr226) Rabbit pAb
-YP0344
主要信息
Target
C/EBP α Phospho Thr226
Host Species
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Applications
WB, ELISA
MW
42kD,also have 30kD isform (Observed)
Conjugate/Modification
Phospho
货号: YP0344
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-C/EBP α (T226) Polyclonal Antibody detects endogenous levels of C/EBP α protein only when phosphorylated at T226.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):HPtPP
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
42kD,also have 30kD isform
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human C/EBP-alpha around the phosphorylation site of Thr226. AA range:192-241
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特异性:
Phospho-C/EBP α (T226) Polyclonal Antibody detects endogenous levels of C/EBP α protein only when phosphorylated at T226.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):HPtPP
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基因名称:
CEBPA
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蛋白名称:
CCAAT/enhancer-binding protein alpha
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别名:
CEBPA ;
CCAAT/enhancer-binding protein alpha ;
C/EBP alpha
CCAAT/enhancer-binding protein alpha ;
C/EBP alpha
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背景:
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013],
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功能:
Function:C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. C/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C/EBP beta and gamma. Interacts with UBN1. Interacts with HBV protein X.,
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细胞定位:
Nucleus .; [Isoform 4]: Nucleus, nucleolus .
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研究领域:
>>Non-alcoholic fatty liver disease ;
>>Pathways in cancer ;
>>Transcriptional misregulation in cancer ;
>>Acute myeloid leukemia
>>Pathways in cancer ;
>>Transcriptional misregulation in cancer ;
>>Acute myeloid leukemia
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信号通路
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货号: YP0344
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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