Synthesized peptide derived from human FCERG AA range: 31-81

This antibody detects endogenous levels of FCERG at Human/Mouse/Rat

FCER1G

FCERG

The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008],

Function:Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface.,similarity:Belongs to the CD3Z/FCER1G family.,similarity:Contains 1 ITAM domain.,subunit:IgE Fc receptor is a tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains. The gamma chain from Fc-epsilon-Ri are also subunits of other Fc receptors like FCGR1A.,

Cell membrane ; Single-pass type I membrane protein .

>>Sphingolipid signaling pathway ;
>>Phospholipase D signaling pathway ;
>>Platelet activation ;
>>C-type lectin receptor signaling pathway ;
>>Natural killer cell mediated cytotoxicity ;
>>Fc epsilon RI signaling pathway ;
>>Tuberculosis ;
>>Asthma