VGLUT1 (PT1164R) PT™ Rabbit mAb
-YM9013
主要信息
Target
VGLU1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, IP, ELISA
MW
62kD (Calculated)
62kD (Observed)
Conjugate/Modification
Unmodified
货号: YM9013
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
62kD
实测条带
62kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT1164R
同种型
IgG,Kappa
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
SLC17A7 BNPI VGLUT1
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蛋白名称:
VGLU1
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别名:
Vesicular glutamate transporter 1 ;
VGluT1 ;
Brain-specific Na ;
+ ;
-dependent inorganic phosphate cotransporter ;
Solute carrier family 17 member 7 ;
VGluT1 ;
Brain-specific Na ;
+ ;
-dependent inorganic phosphate cotransporter ;
Solute carrier family 17 member 7 ;
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背景:
The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008],
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功能:
Function:Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.,similarity:Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.,tissue specificity:Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe.,
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细胞定位:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Membrane ; Multi-pass membrane protein . Cell junction, synapse, synaptosome .
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组织表达:
Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe.
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研究领域:
>>Synaptic vesicle cycle ;
>>Retrograde endocannabinoid signaling ;
>>Glutamatergic synapse ;
>>Nicotine addiction
>>Retrograde endocannabinoid signaling ;
>>Glutamatergic synapse ;
>>Nicotine addiction
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信号通路
文献引用（{{totalcount}}）
货号: YM9013
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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