ATF-3 (PT1162R) PT™ Rabbit mAb
-YM9011
主要信息
Target
ATF-3
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, IP, ELISA
MW
21kD (Calculated)
21kD (Observed)
Conjugate/Modification
Unmodified
货号: YM9011
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
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详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
21kD
实测条带
21kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT1162R
同种型
IgG,Kappa
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
ATF3
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蛋白名称:
Cyclic AMP-dependent transcription factor ATF-3
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别名:
ATF3 ;
Cyclic AMP-dependent transcription factor ATF-3 ;
cAMP-dependent transcription factor ATF-3 ;
Activating transcription factor 3
Cyclic AMP-dependent transcription factor ATF-3 ;
cAMP-dependent transcription factor ATF-3 ;
Activating transcription factor 3
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背景:
activating transcription factor 3(ATF3) Homo sapiens This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes. [provided by RefSeq, Apr 2011],
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功能:
Function:This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. ATF subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a homodimer or a heterodimer.,
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细胞定位:
Nucleus .
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组织表达:
Amygdala,Brain,Cerebellum,Muscle,
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文献引用（{{totalcount}}）
货号: YM9011
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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