SCD (PT0866R) PT® Rabbit mAb
-YM8635
主要信息
Target
ACOD
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, IP, ELISA
MW
42kD (Calculated)
37kD (Observed)
Conjugate/Modification
Unmodified
货号: YM8635
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
42kD
实测条带
37kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0866R
同种型
IgG,Kappa
相关产品
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YM3028
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YM3029
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
SCD
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蛋白名称:
Acyl-CoA desaturase (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase)
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背景:
This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015],
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功能:
Catalytic activity:Stearoyl-CoA + 2 ferrocytochrome b5 + O(2) + 2 H(+) = oleoyl-CoA + 2 ferricytochrome b5 + 2 H(2)O.,cofactor:Iron.,Domain:The histidine box domains may contain the active site and/or be involved in metal ion binding.,Function:Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.,similarity:Belongs to the fatty acid desaturase family.,
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细胞定位:
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
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组织表达:
Detected in fetal liver, lung and brain. Highly expressed in adult adipose tissue, and at lower levels in adult brain and lung.
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研究领域:
>>Biosynthesis of unsaturated fatty acids ;
>>Metabolic pathways ;
>>Fatty acid metabolism ;
>>PPAR signaling pathway ;
>>AMPK signaling pathway ;
>>Alcoholic liver disease
>>Metabolic pathways ;
>>Fatty acid metabolism ;
>>PPAR signaling pathway ;
>>AMPK signaling pathway ;
>>Alcoholic liver disease
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信号通路
文献引用（{{totalcount}}）
货号: YM8635
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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