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R

Musashi-1 (PT0953R) PT™ Rabbit mAb

-YM8256

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主要信息
Target

Msi1

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF, IP, ELISA

MW

39kD (Calculated)

39kD (Observed)

Conjugate/Modification

Unmodified

货号: YM8256
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

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详细信息
推荐稀释比
IHC 1:100-1:400; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
39kD
实测条带
39kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0953R
同种型
IgG,Kappa
RRID号
AB_3698843
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
MSI1
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蛋白名称:
RNA-binding protein Musashi homolog 1
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别名:
MSI1 ;
RNA-binding protein Musashi homolog 1 ;
Musashi-1
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数据库链接:
Organism 基因 ID SwissProt
Human 4440; O43347;
Mouse Q61474;
背景:
This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008],
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功能:
Domain:The first RNA recognition motif binds more strongly to RNA compared to the second one.,Function:RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.,similarity:Belongs to the Musashi family.,similarity:Contains 2 RRM (RNA recognition motif) domains.,tissue specificity:Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.,
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细胞定位:
Cytoplasm . Nucleus .
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组织表达:
Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
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研究领域:
>>mRNA surveillance pathway
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货号: YM8256
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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