xCT (PT0398R) PT® Rabbit mAb
-YM8243
主要信息
Target
SLC7A11
Host Species
Rabbit
Reactivity
Human, Mouse, Rat,
Applications
WB, IHC, IF, IP, ELISA
MW
55kD (Calculated)
37kD (Observed)
Conjugate/Modification
Unmodified
货号: YM8243
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200,
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
55kD
实测条带
37kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0398R
同种型
IgG,Kappa
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
SLC7A11
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蛋白名称:
Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)
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别名:
Cystine/glutamate transporter ;
Amino acid transport system xc- ;
Calcium channel blocker resistance protein CCBR1 ;
Solute carrier family 7 member 11 ;
xCT ;
Amino acid transport system xc- ;
Calcium channel blocker resistance protein CCBR1 ;
Solute carrier family 7 member 11 ;
xCT ;
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背景:
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
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功能:
Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.
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细胞定位:
Membrane
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文献引用（{{totalcount}}）
货号: YM8243
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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