CDC37 (Phospho Ser13) (PT0060R) PT® Rabbit mAb
-YM8031
主要信息
Target
Cdc37
Host Species
Rabbit
Reactivity
Human, Mouse, Rat,
Applications
WB, IHC, IF, IP, ELISA
MW
44kD (Calculated)
44kD (Observed)
Conjugate/Modification
Phospho
货号: YM8031
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
IHC 1:400-1000; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Note:For IHC,wesuggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
This antibody detects endogenous levels of CDC37 only when phosphorylated at Ser13.
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
44kD
实测条带
44kD
修饰
Phospho
克隆性
Monoclonal
克隆号
PT0060R
同种型
IgG,Kappa
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抗原&靶点信息
特异性:
This antibody detects endogenous levels of CDC37 only when phosphorylated at Ser13.
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基因名称:
CDC37
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蛋白名称:
Hsp90 co-chaperone Cdc37
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别名:
CDC37 ;
CDC37A ;
Hsp90 co-chaperone Cdc37 ;
Hsp90 chaperone protein kinase-targeting subunit ;
p50Cdc37
CDC37A ;
Hsp90 co-chaperone Cdc37 ;
Hsp90 chaperone protein kinase-targeting subunit ;
p50Cdc37
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背景:
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008],
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功能:
Function:Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.,PTM:Constitutively sumoylated by UBE2I.,similarity:Belongs to the CDC37 family.,subunit:Forms a complex with Hsp90. Interacts with AR, CDK4, CDK6, EIF2AK1 and RB1.,
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细胞定位:
Cytoplasm
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组织表达:
Lymph,Placenta,
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研究领域:
>>PI3K-Akt signaling pathway
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文献引用（{{totalcount}}）
货号: YM8031
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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